BCG protects against tuberculosis irrespective of HIV status: a matched case-control study in Mwanza, Tanzania.
نویسندگان
چکیده
While BCG vaccine protects against severe tuberculosis (TB) in children, its effect against adult TB is questionable. Furthermore, it is not known if HIV co-infection modifies the effect of BCG. Among 352 pairs of Tanzanian TB cases and matched controls, the BCG scar was associated with a reduced risk of TB (OR 0.3, 95% CI 0.2 to 0.7, p=0.005), irrespective of HIV status (interaction, p=0.623). BCG vaccination considerably reduced the risk of TB, both among individuals with and without HIV infection.
منابع مشابه
BCG vaccine effectiveness in preventing tuberculosis and its interaction with human immunodeficiency virus infection.
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ورودعنوان ژورنال:
- Thorax
دوره 68 3 شماره
صفحات -
تاریخ انتشار 2013